Academic Collaborations

Winzeler 100x100Dr. Elizabeth Winzeler, UC San Diego, co-supports drug screening facility with CDIPD. Her own interests are in drug screens versus the liver stages and gametocytes of malaria. She helps maintain a large insectiary at UCSD from which sporozoites can be harvested from mosquitoes.

Troemel Lab 100x100Dr. Emily Troemel, UC San Diego, uses C. elegans is an experimental model for micorsporidia infection. She is providing key advice and consultation to Dr. Connor Caffrey for his work on the parasitic roundworm, Ancylostoma. Her own work on C. elegans should provide important insights into the cell biology of roundworm parasites that are the free living “cousins" of C. elegans.

LarsEckmann 100x100Dr. Lars Eckmann, UC San Diego, collaborates with CDIPD personnel on drug screens versus both Giardia and Cryptosporidium. He helped validate several hits against Cryptosporidium emerging from CDIPD's collaboration with the Structural Genomics Consortium.

MattCooper 100x100Dr. Matt Cooper, The University of Queensland, Australia. CDIPD has been collaborating with the Cooper laboratory since early 2014 to develop new leads for amebiasis and giardiasis. Cooper group has developed an efficient synthetic approach for a specific compound class and CDIPD is testing those compounds for antiparasitic activity. Dr. Anjan Debnath of CDIPD hosted Angie Jarrad, a PhD student in the Cooper Group for her short-term research at CDIPD.

 

MichaelHsieh 100x100Dr. Michael H. Hsieh. CDIPD has been collaborating with the Hsieh lab to develop a novel point-of-care diagnostic for schistosomiasis.

MomarNdao 100x100Dr. Momar Ndao, McGill University, is an expert on both in vitro screens and animal models of Cryptosporidium. He previously collaborated with CDIPD personnel identifying the major cysteine protease of Cryptosporidium as a valid target for chemotherapy.

SarasLustigman 100x100Dr. Sara Lustigman, New York Blood Center. CDIPD collaborates with the Laboratory of Molecular Parasitology, headed by Sara Lustiman, Ph.D, in filarid parasites, specifically those that cause onchocerciasis, also known as "river blindness", and lymphatic filariasis, also known as elephantiasis. The joint effort is focused, along with Anacor and Rahul Singh, in discovering new therapeutics to treat these diseases.

WilliamRoush 100x100Dr. William Roush, Scripps Florida. CDIPD has been collaborating for years with the Roush laboratory, screening medicinal chemistry series targeting the proteases of T. brucei and T. cruzi in vitro and in vivo. More recently, this collaboration has been extended to include optimization of novel compounds targeting the ergosterol biosynthetic pathway, specifically CYP51, sterol 14-demethylase.